مؤسسة الشرق الأوسط للنشر العلمي
عادةً ما يتم الرد في غضون خمس دقائق
This study investigates the therapeutic potential of vitamin D (cholecalciferol) in inhibiting proliferation and inducing apoptosis in the MCF-7 breast cancer cell line. MCF-7 cells were treated with varying concentrations of vitamin D (0, 10, 50, 100, 200 nM) over 24, 48, and 72 hours. Cellular viability was assessed using MTT assay, and statistical analysis was performed using one-way ANOVA followed by Tukey's post hoc test. Results demonstrated a statistically significant reduction in cell viability in a dose- and time-dependent manner (p < 0.001). These findings suggest that vitamin D exerts anti-proliferative effects on MCF-7 cells, supporting its potential role as an adjuvant therapeutic agent in breast cancer treatment.